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Rutaecarpine targets hERG channels and participates in regulating electrophysiological properties leading to ventricular arrhythmia.
Zhan, Ge; Wang, Fang; Ding, Yun-Qi; Li, Xiang-Hua; Li, Yue-Xin; Zhao, Zheng-Rong; Li, Jia-Xin; Liu, Yan; Zhao, Xin; Yan, Cai-Chuan; Li, Bao-Xin.
Affiliation
  • Zhan G; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Wang F; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Ding YQ; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Li XH; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Li YX; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Zhao ZR; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Li JX; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Liu Y; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Zhao X; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Yan CC; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
  • Li BX; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
J Cell Mol Med ; 25(11): 4938-4949, 2021 06.
Article in En | MEDLINE | ID: mdl-33939251
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Full text: 1 Database: MEDLINE Main subject: Arrhythmias, Cardiac / Quinazolines / Vasodilator Agents / Long QT Syndrome / Action Potentials / Ventricular Dysfunction / Indole Alkaloids / ERG1 Potassium Channel Language: En Journal: J Cell Mol Med Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Arrhythmias, Cardiac / Quinazolines / Vasodilator Agents / Long QT Syndrome / Action Potentials / Ventricular Dysfunction / Indole Alkaloids / ERG1 Potassium Channel Language: En Journal: J Cell Mol Med Year: 2021 Type: Article Affiliation country: China