<i>In Silico</i> Evaluation of Human Cathelicidin LL-37 as a Novel Therapeutic Inhibitor of Panton-Valentine Leukocidin Toxin of Methicillin-Resistant <i>Staphylococcus aureus</i>.

Toor, Himanshu G; Banerjee, Devjani I; Chauhan, Jenabhai B

In Silico Evaluation of Human Cathelicidin LL-37 as a Novel Therapeutic Inhibitor of Panton-Valentine Leukocidin Toxin of Methicillin-Resistant Staphylococcus aureus.

Toor, Himanshu G; Banerjee, Devjani I; Chauhan, Jenabhai B.

Affiliation

Toor HG; P.G. Department of Genetics, Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences (ARIBAS), Sardar Patel University, Anand, India.
Banerjee DI; Dr. Vikram Sarabhai Institute of Cell and Molecular Biology, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, India.
Chauhan JB; P.G. Department of Genetics, Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences (ARIBAS), Sardar Patel University, Anand, India.

Microb Drug Resist ; 27(5): 602-615, 2021 May.

Article in En | MEDLINE | ID: mdl-33983855

Subject(s)

Antimicrobial Cationic Peptides/pharmacology; Bacterial Toxins/antagonists & inhibitors; Exotoxins/antagonists & inhibitors; Leukocidins/antagonists & inhibitors; Methicillin-Resistant Staphylococcus aureus/drug effects; Antimicrobial Cationic Peptides/pharmacokinetics; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Cathelicidins

Key words

MRSA; Panton-Valentine leukocidin; PatchDock; cathelicidin LL-37; molecular docking; toxins

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Plantas_medicinales Main subject: Bacterial Toxins / Antimicrobial Cationic Peptides / Exotoxins / Methicillin-Resistant Staphylococcus aureus / Leukocidins Language: En Journal: Microb Drug Resist Year: 2021 Type: Article Affiliation country: India

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