Pyrazoles and Pyrazolines as Anti-Inflammatory Agents.

Mantzanidou, Martha; Pontiki, Eleni; Hadjipavlou-Litina, Dimitra

Mantzanidou, Martha; Pontiki, Eleni; Hadjipavlou-Litina, Dimitra.

Affiliation

Mantzanidou M; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Pontiki E; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Hadjipavlou-Litina D; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

Molecules ; 26(11)2021 Jun 05.

Article in En | MEDLINE | ID: mdl-34198914

Subject(s)

Anti-Inflammatory Agents/chemical synthesis; Lipoxygenase Inhibitors/chemical synthesis; Lipoxygenase/chemistry; Pyrazoles/chemical synthesis; Animals; Anti-Inflammatory Agents/chemistry; Anti-Inflammatory Agents/pharmacology; Inhibitory Concentration 50; Lipid Peroxidation/drug effects; Lipoxygenase/metabolism; Lipoxygenase Inhibitors/chemistry; Lipoxygenase Inhibitors/pharmacology; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Protein Binding; Pyrazoles/chemistry; Pyrazoles/pharmacology; Rats

Key words

analgesic activity; anti-arthritis; anti-inflammatory activities; antioxidant activities; docking study; lipoxygenase inhibition; pyrazoles; pyrazolines

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Full text: 1 Database: MEDLINE Main subject: Pyrazoles / Lipoxygenase Inhibitors / Lipoxygenase / Anti-Inflammatory Agents Language: En Journal: Molecules Year: 2021 Type: Article Affiliation country: Greece

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