An integrative method based on UHPLC-Q-TOF-MS/MS combined with metabolomics to authenticate Isodon rubescens.

Xie, Weiwei; Ma, Yinghua; Sun, Wenjing; Guan, Shuai; Jin, Yiran; Du, Yingfeng

Xie, Weiwei; Ma, Yinghua; Sun, Wenjing; Guan, Shuai; Jin, Yiran; Du, Yingfeng.

Affiliation

Xie W; The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, PR China.
Ma Y; Children's Hospital of Hebei Province, Shijiazhuang, Hebei, 050031, PR China.
Sun W; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, Shijiazhuang, Hebei, PR China.
Guan S; The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, PR China.
Jin Y; The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, PR China. Electronic address: jinyiran@sohu.com.
Du Y; Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, Shijiazhuang, Hebei, PR China. Electronic address: yingfengdu@hotmail.com.

Anal Biochem ; 629: 114297, 2021 09 15.

Article in En | MEDLINE | ID: mdl-34217704

Subject(s)

Biomarkers/analysis; Diterpenes/analysis; Drugs, Chinese Herbal/analysis; Isodon/chemistry; Chromatography, High Pressure Liquid; Least-Squares Analysis; Medicine, Chinese Traditional; Metabolomics; Multivariate Analysis; Principal Component Analysis; Tandem Mass Spectrometry

Key words

Chemical markers; Genuine regional drug; Isodon rubescens (Hemsl.) hara; Metabolomics approach; UHPLC-Q-TOF-MS/MS

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Drugs, Chinese Herbal / Biomarkers / Isodon / Diterpenes Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Anal Biochem Year: 2021 Type: Article

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