Antiparasitic Properties of Propolis Extracts and Their Compounds.
Chem Biodivers
; 18(9): e2100310, 2021 Sep.
Article
in En
| MEDLINE
| ID: mdl-34231306
ABSTRACT
Propolis is a bee product that has been used in medicine since ancient times. Although its anti-inflammatory, antioxidant, antimicrobial, antitumor, and immunomodulatory activities have been investigated, its anti-parasitic properties remain poorly explored, especially regarding helminths. This review surveys the results obtained with propolis around the world against human parasites. Regarding protozoa, studies carried out with the protozoa Trypanosoma spp. and Leishmania spp. have demonstrated promising results inâ
vitro and inâ
vivo. However, there are fewer studies for Plasmodium spp., the etiological agent of malaria and less so for helminths, particularly for Fasciola spp. and Schistosoma spp. Despite the favorable inâ
vitro results with propolis, helminth assays need to be further investigated. However, propolis has shown itself to be an excellent natural product for parasitology, thus opening new paths and approaches in its activity against protozoa and helminths.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Phenols
/
Propolis
/
Plant Extracts
/
Antiparasitic Agents
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Chem Biodivers
Year:
2021
Type:
Article
Affiliation country:
Brazil