Therapeutic potential of nanoemulsions as feasible wagons for targeting Alzheimer's disease.
Drug Discov Today
; 26(12): 2881-2888, 2021 12.
Article
in En
| MEDLINE
| ID: mdl-34332094
ABSTRACT
Alzheimer's disease (AD) is an irreversible dementia state with characteristic clinical manifestations, including declining cognitive skills and loss of memory, which particularly affects the older population. Despite significant efforts in the field of nano-based drug delivery, there have been few successes achieved in the design of a rational drug therapy. Nanoemulsions (NEs) have potential for the delivery of AD therapeutics owing to their capability for brain drug delivery. Still, there is a long way to go before such therapeutics become a reality in the clinic. In this review, we highlight the preclinical assessment of NEs for AD and discuss the regulatory constraints to their clinical acceptance.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Drug Delivery Systems
/
Nanoparticles
/
Alzheimer Disease
Language:
En
Journal:
Drug Discov Today
Year:
2021
Type:
Article
Affiliation country:
India