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Isoformononetin, a dietary isoflavone protects against streptozotocin induced rat model of neuroinflammation through inhibition of NLRP3/ASC/IL-1 axis activation.
Chaturvedi, Swati; Tiwari, Virendra; Gangadhar, Narwade Mahaveer; Rashid, Mamunur; Sultana, Nazneen; Singh, Sandeep Kumar; Shukla, Shubha; Wahajuddin, Muhammad.
Affiliation
  • Chaturvedi S; Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Tiwari V; Division of Neuroscience and Ageing Biology, Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Gangadhar NM; Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow 226031, India.
  • Rashid M; Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow 226031, India.
  • Sultana N; Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow 226031, India.
  • Singh SK; Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Shukla S; Division of Neuroscience and Ageing Biology, Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
  • Wahajuddin M; Division of Pharmaceutics and Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: wahajuddin@cdri.res.in.
Life Sci ; 286: 119989, 2021 Dec 01.
Article in En | MEDLINE | ID: mdl-34597609
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Full text: 1 Database: MEDLINE Main subject: Interleukin-1 / Streptozocin / Encephalitis / CARD Signaling Adaptor Proteins / NLR Family, Pyrin Domain-Containing 3 Protein / Isoflavones / Antioxidants Type of study: Prognostic_studies Language: En Journal: Life Sci Year: 2021 Type: Article Affiliation country: India
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Full text: 1 Database: MEDLINE Main subject: Interleukin-1 / Streptozocin / Encephalitis / CARD Signaling Adaptor Proteins / NLR Family, Pyrin Domain-Containing 3 Protein / Isoflavones / Antioxidants Type of study: Prognostic_studies Language: En Journal: Life Sci Year: 2021 Type: Article Affiliation country: India