<i>Caragana rosea</i> Turcz Methanol Extract Inhibits Lipopolysaccharide-Induced Inflammatory Responses by Suppressing the TLR4/NF-&#954;B/IRF3 Signaling Pathways.

Mitra, Ankita; Ahuja, Akash; Rahmawati, Laily; Kim, Han Gyung; Woo, Byoung Young; Hong, Yong Deog; Hossain, Mohammad Amjad; Zhang, Zhiyun; Kim, Soo-Yong; Lee, Jongsung; Kim, Jong-Hoon; Cho, Jae Youl

Caragana rosea Turcz Methanol Extract Inhibits Lipopolysaccharide-Induced Inflammatory Responses by Suppressing the TLR4/NF-κB/IRF3 Signaling Pathways.

Mitra, Ankita; Ahuja, Akash; Rahmawati, Laily; Kim, Han Gyung; Woo, Byoung Young; Hong, Yong Deog; Hossain, Mohammad Amjad; Zhang, Zhiyun; Kim, Soo-Yong; Lee, Jongsung; Kim, Jong-Hoon; Cho, Jae Youl.

Affiliation

Mitra A; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Ahuja A; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Rahmawati L; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Kim HG; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Woo BY; AmorePacific R&D Center, Yongin 17074, Korea.
Hong YD; AmorePacific R&D Center, Yongin 17074, Korea.
Hossain MA; Department of Veterinary Physiology, College of Medicine, Chonbuk National University, Iksan 54596, Korea.
Zhang Z; State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, the Chinese Academy of Sciences, Beijing 100093, China.
Kim SY; International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Lee J; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Kim JH; Department of Veterinary Physiology, College of Medicine, Chonbuk National University, Iksan 54596, Korea.
Cho JY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.

Molecules ; 26(21)2021 Nov 03.

Article in En | MEDLINE | ID: mdl-34771068

Subject(s)

Anti-Inflammatory Agents/pharmacology; Caragana/chemistry; Inflammation/drug therapy; Methanol/chemistry; Plant Extracts/pharmacology; Animals; Anti-Inflammatory Agents/chemistry; Anti-Inflammatory Agents/isolation & purification; Cells, Cultured; HEK293 Cells; Humans; Inflammation/chemically induced; Inflammation/metabolism; Interferon Regulatory Factor-3/antagonists & inhibitors; Interferon Regulatory Factor-3/metabolism; Lipopolysaccharides/antagonists & inhibitors; Mice; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; Plant Extracts/chemistry; Plant Extracts/isolation & purification; RAW 264.7 Cells; Signal Transduction/drug effects; Toll-Like Receptor 4/antagonists & inhibitors; Toll-Like Receptor 4/metabolism

Key words

Caragana rosea Turcz (Cr-ME); NF-κB and IRF3 signaling pathways; anti-inflammatory activity

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Full text: 1 Database: MEDLINE Main subject: Plant Extracts / Caragana / Methanol / Inflammation / Anti-Inflammatory Agents Language: En Journal: Molecules Year: 2021 Type: Article

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