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Screening for drugs potentially interfering with MCT8-mediated T3 transport in vitro identifies dexamethasone and some commonly used drugs as inhibitors of MCT8 activity.
Di Cosmo, C; De Marco, G; Agretti, P; Ferrarini, E; Dimida, A; Falcetta, P; Benvenga, S; Vitti, P; Tonacchera, M.
Affiliation
  • Di Cosmo C; Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Pisa, via Paradisa 2, 56124, Pisa, Italy. katiadicosmo@yahoo.it.
  • De Marco G; Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Pisa, via Paradisa 2, 56124, Pisa, Italy.
  • Agretti P; Laboratory of Chemistry and Endocrinology, University Hospital of Pisa, Pisa, Italy.
  • Ferrarini E; Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Pisa, via Paradisa 2, 56124, Pisa, Italy.
  • Dimida A; Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Pisa, via Paradisa 2, 56124, Pisa, Italy.
  • Falcetta P; Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Pisa, via Paradisa 2, 56124, Pisa, Italy.
  • Benvenga S; Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
  • Vitti P; Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Pisa, via Paradisa 2, 56124, Pisa, Italy.
  • Tonacchera M; Department of Clinical and Experimental Medicine, Endocrinology Unit, University of Pisa, via Paradisa 2, 56124, Pisa, Italy.
J Endocrinol Invest ; 45(4): 803-814, 2022 Apr.
Article in En | MEDLINE | ID: mdl-34850364
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Full text: 1 Database: MEDLINE Main subject: Triiodothyronine / Dexamethasone / Monocarboxylic Acid Transporters / Symporters Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: J Endocrinol Invest Year: 2022 Type: Article Affiliation country: Italy
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Full text: 1 Database: MEDLINE Main subject: Triiodothyronine / Dexamethasone / Monocarboxylic Acid Transporters / Symporters Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: J Endocrinol Invest Year: 2022 Type: Article Affiliation country: Italy