Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1&#945;/XBP1 pathway.

Zhang, Xueying; Huo, Zhaojiong; Luan, Huiling; Huang, Yihai; Shen, Yanhui; Sheng, Liang; Liang, Jiangyu; Wu, Feihua

Scutellarin ameliorates hepatic lipid accumulation by enhancing autophagy and suppressing IRE1α/XBP1 pathway.

Zhang, Xueying; Huo, Zhaojiong; Luan, Huiling; Huang, Yihai; Shen, Yanhui; Sheng, Liang; Liang, Jiangyu; Wu, Feihua.

Affiliation

Zhang X; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
Huo Z; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
Luan H; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
Huang Y; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
Shen Y; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
Sheng L; School of Basic Medical Science, Nanjing Medical University, Nanjing, China.
Liang J; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.
Wu F; School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.

Phytother Res ; 36(1): 433-447, 2022 Jan.

Article in En | MEDLINE | ID: mdl-34859513

Subject(s)

Endoribonucleases; Non-alcoholic Fatty Liver Disease; Animals; Apigenin; Autophagy; Fatty Acids; Glucuronates; Inositol; Lipid Metabolism; Mice; Non-alcoholic Fatty Liver Disease/drug therapy; Protein Serine-Threonine Kinases; X-Box Binding Protein 1/genetics

Key words

XBP1s; autophagy; endoplasmic reticulum stress; nonalcoholic fatty liver disease; scutellarin

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Full text: 1 Database: MEDLINE Main subject: Endoribonucleases / Non-alcoholic Fatty Liver Disease Language: En Journal: Phytother Res Year: 2022 Type: Article Affiliation country: China

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