Apigenin Induces Autophagy and Cell Death by Targeting EZH2 under Hypoxia Conditions in Gastric Cancer Cells.

Kim, Tae Woo; Lee, Hee Gu

Kim, Tae Woo; Lee, Hee Gu.

Affiliation

Kim TW; Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Lee HG; Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, 1 Hoegi, Seoul 130-701, Korea.

Int J Mol Sci ; 22(24)2021 Dec 15.

Article in En | MEDLINE | ID: mdl-34948250

Subject(s)

Apigenin/metabolism; Stomach Neoplasms/metabolism; Adenylate Kinase/metabolism; Apigenin/pharmacology; Apoptosis; Autophagic Cell Death/drug effects; Autophagy; Autophagy-Related Protein 5/metabolism; Autophagy-Related Protein-1 Homolog/metabolism; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Stress; Enhancer of Zeste Homolog 2 Protein/metabolism; Humans; Intracellular Signaling Peptides and Proteins/metabolism; Microtubule-Associated Proteins/metabolism; Phosphorylation; RNA-Binding Proteins/metabolism; Signal Transduction; Stomach Neoplasms/physiopathology; TOR Serine-Threonine Kinases/metabolism

Key words

ER stress; apigenin; autophagy; hypoxia; resistance

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Stomach Neoplasms / Apigenin Language: En Journal: Int J Mol Sci Year: 2021 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Stomach Neoplasms / Apigenin Language: En Journal: Int J Mol Sci Year: 2021 Type: Article