Treatment of vitiligo with 308-nm light emitting diode: Our experience from a two-year follow-up of Chinese patients.
Photodermatol Photoimmunol Photomed
; 38(5): 489-494, 2022 Sep.
Article
in En
| MEDLINE
| ID: mdl-35075714
ABSTRACT
BACKGROUND:
A light emitting diode (LED), with a wavelength of 308 nm, has been utilized in the dermatologic treatment of vitiligo.OBJECTIVES:
We investigated the efficacy and safety of 308-nm LED for use in the treatment of vitiligo.METHODS:
We conducted a retrospective study of 70 stable-stage vitiligo patients (with a total of 99 lesions) who received 308-nm LED treatment at the Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College from June 2018 to June 2020. Treatment efficacy was evaluated after 8 treatment sessions, 16 treatment sessions, and the final treatment session, to estimate the percentage of re-pigmentation in the treated area. The Kruskal-Wallis test was used for data analysis.RESULTS:
Based on the final treatment session analysis of all 99 lesions, 0 lesions showed no response, 21 lesions showed poor response, 29 lesions showed moderate response, 23 lesions showed good response, and 26 lesions showed excellent response. The efficacy rate was 49.49%, and there was a significant correlation between the six distinct anatomical regions treated and re-pigmentation grade (χ2 = 13.419, p = .009). Among these regions, facial lesions showed the best response to treatment, while the hands and feet lesions showed the poorest response.CONCLUSIONS:
The clinical efficacy of 308-nm LED treatment is limited based on the treatment area. It demonstrated significant practical application in the treatment of vitiligo.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Pigmentation Disorders
/
Ultraviolet Therapy
/
Vitiligo
Type of study:
Observational_studies
/
Prognostic_studies
Country/Region as subject:
Asia
Language:
En
Journal:
Photodermatol Photoimmunol Photomed
Year:
2022
Type:
Article
Affiliation country:
China