Three new flavonoid glycosides from the aerial parts of Allium sativum L. and their anti-platelet aggregation assessment.
Nat Prod Res
; 36(23): 5940-5949, 2022 Dec.
Article
in En
| MEDLINE
| ID: mdl-35263203
ABSTRACT
Three new flavonoid glycosides, Dasuanxinoside F-H (1-3), were isolated from the aerial parts of Allium sativum, together with eight known compounds which were firstly reported in this plant, including three flavonoid glycosides (4-6) and five phenylethanoid glycosides (7-11). Their structures were identified by UV-vis, IR, 1D and 2D NMR spectra, as well as HR-ESI-MS analyses. The inhibitory effect of the isolated compounds on platelet aggregation induced by adenosine diphosphate (ADP) was evaluated in vitro. The results showed that most compounds displayed different degrees of inhibition. Among them, 2, 5, 8 and 9 exhibited the strongest activity on platelet aggregation.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Garlic
/
Glycosides
Language:
En
Journal:
Nat Prod Res
Year:
2022
Type:
Article
Affiliation country:
China