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Evaluation of in vitro transdermal permeation, mass spectrometric imaging, and in vivo analgesic effects of pregabalin using a pluronic lecithin organogel formulation in mice.
Nagao, Michiru; Tajima, Masataka; Sugiyama, Erika; Shinouchi, Ryosuke; Shibata, Keita; Yoshikawa, Masayuki; Yamamoto, Takushi; Sato, Vilasinee Hirunpanich; Nobe, Koji; Sato, Hitoshi.
Affiliation
  • Nagao M; Division of Pharmacokinetics and Pharmacodynamics, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Tokyo, Japan.
  • Tajima M; Division of Pharmacokinetics and Pharmacodynamics, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Tokyo, Japan.
  • Sugiyama E; Division of Pharmacokinetics and Pharmacodynamics, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Tokyo, Japan.
  • Shinouchi R; Division of Pharmacology, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Tokyo, Japan.
  • Shibata K; Pharmacological Research Center, Showa University, Tokyo, Japan.
  • Yoshikawa M; Division of Pharmacology, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Tokyo, Japan.
  • Yamamoto T; Pharmacological Research Center, Showa University, Tokyo, Japan.
  • Sato VH; Division of Pharmacokinetics and Pharmacodynamics, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy, Showa University, Tokyo, Japan.
  • Nobe K; Global Application Development Center, Analytical and Measuring Instruments Division, Shimadzu Corporation, Kyoto, Japan.
  • Sato H; Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Pharmacol Res Perspect ; 10(2): e00919, 2022 04.
Article in En | MEDLINE | ID: mdl-35306752
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Full text: 1 Database: MEDLINE Main subject: Poloxamer / Lecithins Language: En Journal: Pharmacol Res Perspect Year: 2022 Type: Article Affiliation country: Japan
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Full text: 1 Database: MEDLINE Main subject: Poloxamer / Lecithins Language: En Journal: Pharmacol Res Perspect Year: 2022 Type: Article Affiliation country: Japan