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Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 Mpro/3CLpro in Living Cells.
Moghadasi, Seyed Arad; Esler, Morgan A; Otsuka, Yuka; Becker, Jordan T; Moraes, Sofia N; Anderson, Constance B; Chamakuri, Srinivas; Belica, Christopher; Wick, Chloe; Harki, Daniel A; Young, Damian W; Scampavia, Louis; Spicer, Timothy P; Shi, Ke; Aihara, Hideki; Brown, William L; Harris, Reuben S.
Affiliation
  • Moghadasi SA; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Esler MA; Masonic Cancer Center, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Otsuka Y; Institute for Molecular Virology, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Becker JT; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Moraes SN; Institute for Molecular Virology, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Anderson CB; Department of Molecular Medicine, Scripps Research, The Scripps Research Molecular Screening Center, Jupiter, Florida, USA.
  • Chamakuri S; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Belica C; Masonic Cancer Center, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Wick C; Institute for Molecular Virology, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Harki DA; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Young DW; Masonic Cancer Center, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Scampavia L; Institute for Molecular Virology, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Spicer TP; Department of Medicinal Chemistry, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Shi K; Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, USA.
  • Aihara H; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Brown WL; Masonic Cancer Center, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
  • Harris RS; Institute for Molecular Virology, University of Minnesotagrid.17635.36, Minneapolis, Minnesota, USA.
mBio ; 13(3): e0078422, 2022 06 28.
Article in En | MEDLINE | ID: mdl-35471084
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Protease Inhibitors / Coronavirus 3C Proteases / SARS-CoV-2 Language: En Journal: MBio Year: 2022 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Protease Inhibitors / Coronavirus 3C Proteases / SARS-CoV-2 Language: En Journal: MBio Year: 2022 Type: Article Affiliation country: United States