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Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
Meçe, Odeta; Houbaert, Diede; Sassano, Maria-Livia; Durré, Tania; Maes, Hannelore; Schaaf, Marco; More, Sanket; Ganne, Maarten; García-Caballero, Melissa; Borri, Mila; Verhoeven, Jelle; Agrawal, Madhur; Jacobs, Kathryn; Bergers, Gabriele; Blacher, Silvia; Ghesquière, Bart; Dewerchin, Mieke; Swinnen, Johan V; Vinckier, Stefan; Soengas, María S; Carmeliet, Peter; Noël, Agnès; Agostinis, Patrizia.
Affiliation
  • Meçe O; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Houbaert D; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • Sassano ML; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Durré T; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • Maes H; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Schaaf M; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • More S; Laboratory of Tumor and Development Biology, GIGA (GIGA-Cancer), Liege University, B23, Avenue Hippocrate 13, 4000, Liege, Belgium.
  • Ganne M; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • García-Caballero M; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Borri M; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • Verhoeven J; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Agrawal M; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • Jacobs K; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Bergers G; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • Blacher S; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Ghesquière B; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium.
  • Dewerchin M; Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Swinnen JV; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium.
  • Vinckier S; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Soengas MS; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • Carmeliet P; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
  • Noël A; VIB Center for Cancer Biology Research, 3000, Leuven, Belgium.
  • Agostinis P; Cell Death Research and Therapy Group, Department of Cellular and Molecular Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Nat Commun ; 13(1): 2760, 2022 05 19.
Article in En | MEDLINE | ID: mdl-35589749
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Full text: 1 Database: MEDLINE Main subject: Lymphatic Vessels / Lymphangiogenesis Language: En Journal: Nat Commun Year: 2022 Type: Article Affiliation country: Belgium
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Full text: 1 Database: MEDLINE Main subject: Lymphatic Vessels / Lymphangiogenesis Language: En Journal: Nat Commun Year: 2022 Type: Article Affiliation country: Belgium