[Development of a novel aptamer blocking the interaction between the VWF A1 domain and platelet GP Ib for the treatment of arterial thrombosis].

Matsumoto, Masanori; Harada, Kaori

Matsumoto, Masanori; Harada, Kaori.

Affiliation

Matsumoto M; Department of Blood Transfusion Medicine, Nara Medical University.
Harada K; TAGCyx Biotechnologies Inc.

Rinsho Ketsueki ; 63(5): 393-402, 2022.

Article in Ja | MEDLINE | ID: mdl-35662162

Subject(s)

Purpura, Thrombotic Thrombocytopenic; Thrombosis; Blood Platelets; Humans; Platelet Aggregation Inhibitors/therapeutic use; Purpura, Thrombotic Thrombocytopenic/drug therapy; Thrombosis/drug therapy; von Willebrand Factor/therapeutic use

Key words

Aptamer; Oligonucleotide therapeutics; Thrombotic thrombocytopenic purpura (TTP); von Willebrand factor (VWF)

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Full text: 1 Database: MEDLINE Main subject: Purpura, Thrombotic Thrombocytopenic / Thrombosis Language: Ja Journal: Rinsho Ketsueki Year: 2022 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Purpura, Thrombotic Thrombocytopenic / Thrombosis Language: Ja Journal: Rinsho Ketsueki Year: 2022 Type: Article