Scopolin obtained from Smilax china L. against hepatocellular carcinoma by inhibiting glycolysis: A network pharmacology and experimental study.

Wang, Chen; Zhou, Qin; Wu, Song-Tao

Wang, Chen; Zhou, Qin; Wu, Song-Tao.

Affiliation

Wang C; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, 430065, China. Electronic address: Wcc_up@163.com.
Zhou Q; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Wu ST; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China. Electronic address: songt1wu@hbtcm.edu.cn.

J Ethnopharmacol ; 296: 115469, 2022 Oct 05.

Article in En | MEDLINE | ID: mdl-35718053

Subject(s)

Carcinoma, Hepatocellular; Liver Neoplasms; Smilax; Carcinoma, Hepatocellular/drug therapy; Carcinoma, Hepatocellular/metabolism; Coumarins; Glucosides; Glycolysis; Humans; Liver Neoplasms/drug therapy; Liver Neoplasms/metabolism; Molecular Docking Simulation; Network Pharmacology; Plant Extracts/pharmacology; Smilax/chemistry

Key words

Anti-hepatocellular carcinoma; Glycolysis; Microscale thermophoresis; Natural product; Protein binding; Transcriptomics

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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Smilax / Liver Neoplasms Language: En Journal: J Ethnopharmacol Year: 2022 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Smilax / Liver Neoplasms Language: En Journal: J Ethnopharmacol Year: 2022 Type: Article