Inhibitory effect of bushen huoxue formula against dehydroepiandrosterone-induced inflammation in granulosa cells through TLR4/NF-&#954;B signaling pathway.

Jin, Wenqi; Wang, Chaonan; Cui, Minghua; Wang, Manying; Fu, Baoyu; Sun, Liwei; Chen, Xin

Inhibitory effect of bushen huoxue formula against dehydroepiandrosterone-induced inflammation in granulosa cells through TLR4/NF-κB signaling pathway.

Jin, Wenqi; Wang, Chaonan; Cui, Minghua; Wang, Manying; Fu, Baoyu; Sun, Liwei; Chen, Xin.

Affiliation

Jin W; Research Center of Traditional Chinese Medicine, the Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, PR China/ College of Pharmacy, Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin, PR China.
Wang C; College of Pharmacy, Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin, PR China.
Cui M; Department of Obstetrics and Gynecology, the Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, PR China.
Wang M; Research Center of Traditional Chinese Medicine, the Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, PR China.
Fu B; College of Pharmacy, Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin, PR China.
Sun L; Research Center of Traditional Chinese Medicine, the Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, PR China.
Chen X; Department of Obstetrics and Gynecology, the Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, PR China.

Pak J Pharm Sci ; 35(3): 701-710, 2022 May.

Article in En | MEDLINE | ID: mdl-35791467

Subject(s)

NF-kappa B; Polycystic Ovary Syndrome; Androgens/metabolism; Androgens/pharmacology; Androgens/therapeutic use; Cytokines/metabolism; Dehydroepiandrosterone/metabolism; Dehydroepiandrosterone/pharmacology; Dehydroepiandrosterone/therapeutic use; Drugs, Chinese Herbal; Female; Granulosa Cells/metabolism; Humans; Inflammation/metabolism; NF-kappa B/metabolism; Polycystic Ovary Syndrome/chemically induced; Polycystic Ovary Syndrome/drug therapy; Polycystic Ovary Syndrome/metabolism; Reproducibility of Results; Signal Transduction; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Polycystic Ovary Syndrome / NF-kappa B Type of study: Prognostic_studies Language: En Journal: Pak J Pharm Sci Year: 2022 Type: Article

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