The Current State-of-the-Art Identification of Unknown Proteins Using Mass Spectrometry Exemplified on De Novo Sequencing of a Venom Protease from <i>Bothrops moojeni</i>.

König, Simone; Obermann, Wolfgang M J; Eble, Johannes A

The Current State-of-the-Art Identification of Unknown Proteins Using Mass Spectrometry Exemplified on De Novo Sequencing of a Venom Protease from Bothrops moojeni.

König, Simone; Obermann, Wolfgang M J; Eble, Johannes A.

Affiliation

König S; IZKF Core Unit Proteomics, Interdisciplinary Center for Clinical Research, University of Münster, Röntgenstr. 21, 48149 Münster, Germany.
Obermann WMJ; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyer-Str. 15, 48149 Münster, Germany.
Eble JA; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyer-Str. 15, 48149 Münster, Germany.

Molecules ; 27(15)2022 Aug 05.

Article in En | MEDLINE | ID: mdl-35956926

Subject(s)

Bothrops; Amino Acids/metabolism; Animals; Bothrops/metabolism; Humans; Peptide Hydrolases/metabolism; Peptides/chemistry; Proteins/chemistry; Snake Venoms/metabolism; Tandem Mass Spectrometry/methods

Key words

CID; MS/MS; gas phase peptide ion fragmentation; mass spectrometry; snake venom; spectrum quality

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Full text: 1 Database: MEDLINE Main subject: Bothrops Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: Molecules Year: 2022 Type: Article Affiliation country: Germany

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