LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages.

Wei, Zheng; Oh, Joonseok; Flavell, Richard A; Crawford, Jason M

Wei, Zheng; Oh, Joonseok; Flavell, Richard A; Crawford, Jason M.

Affiliation

Wei Z; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Oh J; Institute of Biomolecular Design & Discovery, Yale University, West Haven, CT, USA.
Flavell RA; Institute of Biomolecular Design & Discovery, Yale University, West Haven, CT, USA.
Crawford JM; Department of Chemistry, Yale University, New Haven, CT, USA.

Nature ; 609(7926): 348-353, 2022 09.

Article in En | MEDLINE | ID: mdl-35978195

Subject(s)

Inflammation; Intracellular Signaling Peptides and Proteins; Macrophages; Nitric Oxide Synthase Type II; Animals; Arthritis/immunology; Arthritis/metabolism; Citrulline/metabolism; Cyanates/metabolism; Humans; Inflammation/enzymology; Inflammation/immunology; Inflammation/metabolism; Inflammatory Bowel Diseases/immunology; Inflammatory Bowel Diseases/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; Macrophages/immunology; Macrophages/metabolism; Mice; Nitric Oxide Synthase Type II/metabolism; Ornithine/metabolism; Ornithine Decarboxylase/metabolism; Polyamines/metabolism; Salmonella typhimurium/immunology

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Full text: 1 Database: MEDLINE Complementary Medicines: Homeopatia Main subject: Intracellular Signaling Peptides and Proteins / Nitric Oxide Synthase Type II / Inflammation / Macrophages Type of study: Prognostic_studies Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: United States

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