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Pharmacologic characterization of TBP1901, a prodrug form of aglycone curcumin, and CRISPR-Cas9 screen for therapeutic targets of aglycone curcumin.
Abe, Tomoyuki; Horisawa, Yoshihito; Kikuchi, Osamu; Ozawa-Umeta, Hitomi; Kishimoto, Atsuhiro; Katsuura, Yasuhiro; Imaizumi, Atsushi; Hashimoto, Tadashi; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Yusa, Kosuke; Asakura, Tadashi; Kakeya, Hideaki; Kanai, Masashi.
Affiliation
  • Abe T; Therabiopharma Inc., Kanagawa, Japan.
  • Horisawa Y; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Kikuchi O; Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Ozawa-Umeta H; Therabiopharma Inc., Kanagawa, Japan.
  • Kishimoto A; Therabiopharma Inc., Kanagawa, Japan.
  • Katsuura Y; Therabiopharma Inc., Kanagawa, Japan.
  • Imaizumi A; Therabiopharma Inc., Kanagawa, Japan.
  • Hashimoto T; Therabiopharma Inc., Kanagawa, Japan.
  • Shirakawa K; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Takaori-Kondo A; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Yusa K; Stem Cell Genetics, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Asakura T; Radioisotope Research Facilities, Jikei University School of Medicine, Tokyo, Japan.
  • Kakeya H; Department of System Chemotherapy and Molecular Sciences, Division of Medicinal Frontier Sciences, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. Electronic address: scseigyo-hisyo@pharm.kyoto-u.ac.jp.
  • Kanai M; Department of Therapeutic Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address: kanai@kuhp.kyoto-u.ac.jp.
Eur J Pharmacol ; 935: 175321, 2022 Nov 15.
Article in En | MEDLINE | ID: mdl-36228744
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia / Plantas_medicinales Main subject: Prodrugs / Curcumin Language: En Journal: Eur J Pharmacol Year: 2022 Type: Article Affiliation country: Japan
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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Aromoterapia / Plantas_medicinales Main subject: Prodrugs / Curcumin Language: En Journal: Eur J Pharmacol Year: 2022 Type: Article Affiliation country: Japan