Qian Yang Yu Yin granule improves hypertensive renal damage: A potential role for TRPC6-CaMKKß-AMPK-mTOR-mediated autophagy.

Ma, Siqi; Xu, Junyao; Zheng, Yawei; Li, Yin; Wang, Yixuan; Li, Haitao; Fang, Zhuyuan; Li, Jie

Ma, Siqi; Xu, Junyao; Zheng, Yawei; Li, Yin; Wang, Yixuan; Li, Haitao; Fang, Zhuyuan; Li, Jie.

Affiliation

Ma S; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: maqisi@126.com.
Xu J; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China; The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: xujunyao313@163.com.
Zheng Y; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China; The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: villis77@outlook.com.
Li Y; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: lee1708@163.com.
Wang Y; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: wangyx0844@163.com.
Li H; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: lihaitao0003@sina.com.
Fang Z; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: fangzhuyuan@njucm.edu.cn.
Li J; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. Electronic address: jellylee8803@126.com.

J Ethnopharmacol ; 302(Pt A): 115878, 2023 Feb 10.

Article in En | MEDLINE | ID: mdl-36341814

Subject(s)

Hypertension; Podocytes; Animals; Rats; Calcium-Calmodulin-Dependent Protein Kinase Kinase/metabolism; TRPC6 Cation Channel/metabolism; AMP-Activated Protein Kinases/metabolism; Calcium/metabolism; Autophagy; TOR Serine-Threonine Kinases/metabolism; Angiotensin II/metabolism; Hypertension/drug therapy; Hypertension/metabolism; TRPC Cation Channels/genetics; TRPC Cation Channels/metabolism; TRPC Cation Channels/pharmacology

Key words

Autophagy; Hypertensive renal damage; Podocyte; Qian Yang Yu Yin granule; TRPC6-CaMKKß-AMPK-mTOR pathway

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Podocytes / Hypertension Language: En Journal: J Ethnopharmacol Year: 2023 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google