Unveiling the vulnerabilities of synthetic lethality in triple-negative breast cancer.

Chatterjee, Prarthana; Karn, Rohit; Isaac, Arnold Emerson; Ray, Smita

Chatterjee, Prarthana; Karn, Rohit; Isaac, Arnold Emerson; Ray, Smita.

Affiliation

Chatterjee P; Department of Botany, Bethune College, Kolkata, West Bengal, 700006, India.
Karn R; School of BioSciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
Isaac AE; School of BioSciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
Ray S; Department of Botany, Bethune College, Kolkata, West Bengal, 700006, India. smitaray2008@gmail.com.

Clin Transl Oncol ; 25(11): 3057-3072, 2023 Nov.

Article in En | MEDLINE | ID: mdl-37079210

Subject(s)

Triple Negative Breast Neoplasms; Humans; Triple Negative Breast Neoplasms/pathology; Synthetic Lethal Mutations; Neoplasm Recurrence, Local/drug therapy; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use; Mutation

Key words

BRCAness; Epidrugs; Epigenetic crosstalks; Poly (ADP-ribose) polymerase inhibitors (PARPi); Synthetic lethality; Translational medicine; Triple-negative breast cancer (TNBC)

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Full text: 1 Database: MEDLINE Main subject: Triple Negative Breast Neoplasms Type of study: Prognostic_studies Language: En Journal: Clin Transl Oncol Year: 2023 Type: Article Affiliation country: India

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