Discovery of effective combination from Renshen-Fuzi herbal pair against heart failure by spectrum-effect relationship analysis and zebrafish models.

Li, Chu-Jun; Zhai, Rong-Rong; Zhu, Xiao-Yu; Guo, Zi-Fan; Yang, Hua

Li, Chu-Jun; Zhai, Rong-Rong; Zhu, Xiao-Yu; Guo, Zi-Fan; Yang, Hua.

Affiliation

Li CJ; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China.
Zhai RR; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China.
Zhu XY; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China.
Guo ZF; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China.
Yang H; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, China. Electronic address: 104yang104@163.com.

J Ethnopharmacol ; 317: 116832, 2023 Dec 05.

Article in En | MEDLINE | ID: mdl-37352946

Subject(s)

Aconitum; Alkaloids; Drugs, Chinese Herbal; Ginsenosides; Heart Failure; Panax; Animals; Zebrafish; Tandem Mass Spectrometry/methods; Drugs, Chinese Herbal/pharmacology; Drugs, Chinese Herbal/therapeutic use; Drugs, Chinese Herbal/analysis; Alkaloids/pharmacology; Alkaloids/therapeutic use; Alkaloids/analysis; Heart Failure/drug therapy; Aconitum/chemistry

Key words

Aconite root; Ginseng; Heart failure; Mass spectrometry; Spectrum-effect relationship; Zebrafish

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Drugs, Chinese Herbal / Aconitum / Ginsenosides / Alkaloids / Panax / Heart Failure Type of study: Prognostic_studies Language: En Journal: J Ethnopharmacol Year: 2023 Type: Article Affiliation country: China

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