Engineering a triple-functional magnetic gel driving mutually-synergistic mild hyperthermia-starvation therapy for osteosarcoma treatment and augmented bone regeneration.

Yu, Kexiao; Zhou, Hang; Xu, Yamei; Cao, Youde; Zheng, Yuanyi; Liang, Bing

Yu, Kexiao; Zhou, Hang; Xu, Yamei; Cao, Youde; Zheng, Yuanyi; Liang, Bing.

Affiliation

Yu K; Department of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Seventh Branch Road, Jiangbei District, Chongqing, 400021, P. R. China.
Zhou H; Department of Orthopedics, Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong Distinct, Chongqing, 400010, P. R. China.
Xu Y; State Key Laboratory of Ultrasound in Medicine and Engineering, Institute of Ultrasound Imaging, Chongqing Medical University, Chongqing, 400010, People's Republic of China.
Cao Y; Department of Pathology, College of Basic Medicine, Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, 1 Yixueyuan Road, Yuzhong Distinct, Chongqing, 400016, P.R. China.
Zheng Y; Department of Pathology, College of Basic Medicine, Molecular Medicine Diagnostic and Testing Center, Chongqing Medical University, 1 Yixueyuan Road, Yuzhong Distinct, Chongqing, 400016, P.R. China.
Liang B; Department of Ultrasound in Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Xuhui Distinct, Shanghai, 200233, P. R. China. zhengyuanyi@163.com.

J Nanobiotechnology ; 21(1): 201, 2023 Jun 26.

Article in En | MEDLINE | ID: mdl-37365598

Subject(s)

Bone Neoplasms; Hyperthermia, Induced; Osteosarcoma; Mice; Animals; Rabbits; Osteogenesis; Bone Neoplasms/therapy; Bone Neoplasms/metabolism; Osteosarcoma/therapy; Osteosarcoma/metabolism; Bone Regeneration; Heat-Shock Proteins/metabolism; Magnetic Phenomena; Adenosine Triphosphate; Cell Line, Tumor; Tumor Microenvironment

Key words

Bone regeneration; Mild hyperthermia therapy; Osteosarcoma; Starvation therapy; Triple-functional magnetic hydrogels

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma / Hyperthermia, Induced Language: En Journal: J Nanobiotechnology Year: 2023 Type: Article

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Bone Neoplasms / Osteosarcoma / Hyperthermia, Induced Language: En Journal: J Nanobiotechnology Year: 2023 Type: Article