[Compound Tinglizi Decoction intervenes COPD-associated pulmonary hypertension through regulation of HMGB1-mediated pyroptosis and immune imbalance].

Wu, Xin-Cheng; Liu, Yu; Bai, Zheng-Ping

Wu, Xin-Cheng; Liu, Yu; Bai, Zheng-Ping.

Affiliation

Wu XC; Hunan University of Chinese Medicine Changsha 410208, China Department of Pulmonary and Critical Care Medicine,Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine Nanning 530011, China.
Liu Y; the Affilited Hospital of Hunan Academy of Traditional Chinese Medicine Changsha 410006, China.
Bai ZP; Hunan University of Chinese Medicine Changsha 410208, China Hunan Academy of Chinese Medicine Changsha 410006, China.

Zhongguo Zhong Yao Za Zhi ; 48(11): 3055-3065, 2023 Jun.

Article in Zh | MEDLINE | ID: mdl-37381964

Subject(s)

HMGB1 Protein; Hypertension, Pulmonary; Pulmonary Disease, Chronic Obstructive; Animals; Rats; Caspase 8; Pyroptosis; HMGB1 Protein/genetics; Hypertension, Pulmonary/drug therapy; Hypertension, Pulmonary/etiology; Pulmonary Disease, Chronic Obstructive/drug therapy; Pulmonary Disease, Chronic Obstructive/genetics

Key words

Compound Tinglizi Decoction; caspase-8; chronic obstructive pulmonary disease-associated pulmonary hypertension(COPD-PH); high mobility group box 1(HMGB1); immune imbalance; pyroptosis

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Full text: 1 Database: MEDLINE Main subject: Pulmonary Disease, Chronic Obstructive / HMGB1 Protein / Hypertension, Pulmonary Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: Zh Journal: Zhongguo Zhong Yao Za Zhi Year: 2023 Type: Article Affiliation country: China

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