Serum metabolome profiling, network pharmacology analysis, and experimental validation of Anoectochilus roxburghii in the treatment of carbon tetrachloride-induced liver injury.

Tao, Yi; Yang, Ying; Zhu, Fei; Wu, Mei; Kong, Xiangjun; Wang, Ping

Tao, Yi; Yang, Ying; Zhu, Fei; Wu, Mei; Kong, Xiangjun; Wang, Ping.

Affiliation

Tao Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Yang Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Zhu F; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
Wu M; Jinhua Academy of Agricultural Sciences, Jinhua, China.
Kong X; Jinhua Academy of Agricultural Sciences, Jinhua, China.
Wang P; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.

Biomed Chromatogr ; 37(10): e5706, 2023 Oct.

Article in En | MEDLINE | ID: mdl-37491783

Subject(s)

Chemical and Drug Induced Liver Injury, Chronic; Chemical and Drug Induced Liver Injury; Rats; Male; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury, Chronic/metabolism; Alkaline Phosphatase; Alanine Transaminase; Network Pharmacology; Rats, Sprague-Dawley; Chemical and Drug Induced Liver Injury/metabolism; Liver/metabolism; Plant Extracts; Metabolome; Aspartate Aminotransferases

Key words

Anoectochilus roxburghii (Wall.) Lindl; liver injury; network pharmacology; serum metabolomics

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Full text: 1 Database: MEDLINE Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Chemical and Drug Induced Liver Injury / Chemical and Drug Induced Liver Injury, Chronic Language: En Journal: Biomed Chromatogr Year: 2023 Type: Article Affiliation country: China

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