Inhibitory Effects of Polyphenol- and Flavonoid-Enriched Rice Seed Extract on Melanogenesis in Melan-a Cells via MAPK Signaling-Mediated MITF Downregulation.

Monmai, Chaiwat; Kim, Jin-Suk; Chin, Joong Hyoun; Lee, Sanghyun; Baek, So-Hyeon

Monmai, Chaiwat; Kim, Jin-Suk; Chin, Joong Hyoun; Lee, Sanghyun; Baek, So-Hyeon.

Affiliation

Monmai C; Department of Agricultural Life Science, Sunchon National University, Suncheon 59722, Republic of Korea.
Kim JS; Department of Agricultural Life Science, Sunchon National University, Suncheon 59722, Republic of Korea.
Chin JH; Department of Integrative Biological Sciences and Industry, Sejong University, Seoul 05006, Republic of Korea.
Lee S; Department of Plant Science and Technology, Chung-Ang University, Anseong 17546, Republic of Korea.
Baek SH; Department of Agricultural Life Science, Sunchon National University, Suncheon 59722, Republic of Korea.

Int J Mol Sci ; 24(14)2023 Jul 24.

Article in En | MEDLINE | ID: mdl-37511600

Subject(s)

Melanins; Oryza; Melanins/metabolism; Flavonoids/pharmacology; Polyphenols/pharmacology; Down-Regulation; Oryza/metabolism; Signal Transduction; Microphthalmia-Associated Transcription Factor/metabolism; MART-1 Antigen/metabolism; MART-1 Antigen/pharmacology; Ultraviolet Rays; Monophenol Monooxygenase/metabolism; Plant Extracts/pharmacology; Cell Line, Tumor

Key words

MAPK pathway; MITF; PI3K/Akt pathway; anti-melanogenic; antioxidant; flavonoids; melanogenesis; polyphenols; tyrosinase activity

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Full text: 1 Database: MEDLINE Main subject: Oryza / Melanins Language: En Journal: Int J Mol Sci Year: 2023 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Oryza / Melanins Language: En Journal: Int J Mol Sci Year: 2023 Type: Article