QbD-Guided Traditional Chinese Medicine Manufacturing Process: Development and Optimization of Fluid-Bed Granulation and Drying Processes for Xiaochaihu Capsules.

Teng, Kaixuan; Fu, Hao; Wu, Gelin; Gong, Ping; Xie, Yongjian; Zhou, Peng; Gong, Xingchu; Qu, Haibin

Teng, Kaixuan; Fu, Hao; Wu, Gelin; Gong, Ping; Xie, Yongjian; Zhou, Peng; Gong, Xingchu; Qu, Haibin.

Affiliation

Teng K; Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Fu H; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou, 310018, China.
Wu G; Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Gong P; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou, 310018, China.
Xie Y; Zhejiang Pralife Pharmaceutical Co., Ltd., Taizhou, 318000, China.
Zhou P; Zhejiang Pralife Pharmaceutical Co., Ltd., Taizhou, 318000, China.
Gong X; Zhejiang Pralife Pharmaceutical Co., Ltd., Taizhou, 318000, China.
Qu H; Zhejiang Pralife Pharmaceutical Co., Ltd., Taizhou, 318000, China.

AAPS PharmSciTech ; 24(7): 210, 2023 Oct 11.

Article in En | MEDLINE | ID: mdl-37821749

Subject(s)

Drugs, Chinese Herbal; Medicine, Chinese Traditional; Desiccation/methods; Risk Assessment

Key words

Xiaochaihu (XCH); definitive screening design (DSD); fluid-bed granulation (FBG); quality by design (QbD); traditional Chinese medicine (TCM)

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Therapeutic Methods and Therapies TCIM: Terapias_biologicas Main subject: Drugs, Chinese Herbal / Medicine, Chinese Traditional Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: AAPS PharmSciTech Year: 2023 Type: Article Affiliation country: China

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google