Dichapetalin-type triterpenoids from Dichapetalum longipetalum and their anti-inflammatory activity.
Phytochemistry
; 217: 113900, 2024 Jan.
Article
in En
| MEDLINE
| ID: mdl-37898415
ABSTRACT
A phytochemical research on the twigs of Dichapetalum longipetalum (Turcz.) Engl. Resulted in five undescribed dichapetalin-type triterpenoids 1-5. Their chemical structures were determined by spectroscopic analysis of HR-ESIMS and NMR spectra and the absolute configuration of compound 1 was completely elucidated by single crystal X-ray crystallography. Through preliminary anti-inflammatory activity assessment, compound 1 exhibited inhibitory effect on LPS-induced NO production in RAW264.7 murine macrophages with an IC50 value of 2.09 µM.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Triterpenes
Language:
En
Journal:
Phytochemistry
Year:
2024
Type:
Article