Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies.

Hong, Jing Han; Yong, Chern Han; Heng, Hong Lee; Chan, Jason Yongsheng; Lau, Mai Chan; Chen, Jianfeng; Lee, Jing Yi; Lim, Abner Herbert; Li, Zhimei; Guan, Peiyong; Chu, Pek Lim; Boot, Arnoud; Ng, Sheng Rong; Yao, Xiaosai; Wee, Felicia Yu Ting; Lim, Jeffrey Chun Tatt; Liu, Wei; Wang, Peili; Xiao, Rong; Zeng, Xian; Sun, Yichen; Koh, Joanna; Kwek, Xiu Yi; Ng, Cedric Chuan Young; Klanrit, Poramate; Zhang, Yaojun; Lai, Jiaming; Tai, David Wai Meng; Pairojkul, Chawalit; Dima, Simona; Popescu, Irinel; Hsieh, Sen-Yung; Yu, Ming-Chin; Yeong, Joe; Kongpetch, Sarinya; Jusakul, Apinya; Loilome, Watcharin; Tan, Patrick; Tan, Jing; Teh, Bin Tean

Hong, Jing Han; Yong, Chern Han; Heng, Hong Lee; Chan, Jason Yongsheng; Lau, Mai Chan; Chen, Jianfeng; Lee, Jing Yi; Lim, Abner Herbert; Li, Zhimei; Guan, Peiyong; Chu, Pek Lim; Boot, Arnoud; Ng, Sheng Rong; Yao, Xiaosai; Wee, Felicia Yu Ting; Lim, Jeffrey Chun Tatt; Liu, Wei; Wang, Peili; Xiao, Rong; Zeng, Xian; Sun, Yichen; Koh, Joanna; Kwek, Xiu Yi; Ng, Cedric Chuan Young; Klanrit, Poramate; Zhang, Yaojun; Lai, Jiaming; Tai, David Wai Meng; Pairojkul, Chawalit; Dima, Simona; Popescu, Irinel; Hsieh, Sen-Yung; Yu, Ming-Chin; Yeong, Joe; Kongpetch, Sarinya; Jusakul, Apinya; Loilome, Watcharin; Tan, Patrick; Tan, Jing; Teh, Bin Tean.

Affiliation

Hong JH; Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, Singapore.
Yong CH; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Heng HL; Department of Computer Science, National University of Singapore, Singapore.
Chan JY; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Lau MC; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Chen J; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore.
Lee JY; Oncology Academic Clinical Program, Duke-NUS Medical School, Singapore.
Lim AH; Singapore Immunology Network, Agency for Science Technology and Research (A*STAR), Singapore.
Li Z; Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), Singapore.
Guan P; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chu PL; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Boot A; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore.
Ng SR; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Yao X; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore.
Wee FYT; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Lim JCT; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore.
Liu W; Genome Institute of Singapore, Agency for Science Technology and Research (A*STAR), Singapore.
Wang P; Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, Singapore.
Xiao R; Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, Singapore.
Zeng X; Centre for Computational Biology, Duke-NUS Medical School, Singapore.
Sun Y; Institute of Molecular and Cell Biology, Agency for Science Technology and Research (A*STAR), Singapore.
Koh J; Institute of Molecular and Cell Biology, Agency for Science Technology and Research (A*STAR), Singapore.
Kwek XY; Institute of Molecular and Cell Biology, Integrative Biology for Theranostics Lab, Agency for Science Technology and Research (A*STAR), Singapore.
Ng CCY; Institute of Molecular and Cell Biology, Integrative Biology for Theranostics Lab, Agency for Science Technology and Research (A*STAR), Singapore.
Klanrit P; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Zhang Y; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Lai J; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Tai DWM; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Pairojkul C; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Dima S; Institute of Molecular and Cell Biology, Agency for Science Technology and Research (A*STAR), Singapore.
Popescu I; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Hsieh SY; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore.
Yu MC; Cancer Discovery Hub, National Cancer Centre Singapore, Singapore.
Yeong J; Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand.
Kongpetch S; Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Jusakul A; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.
Loilome W; Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong.
Tan P; Department of Pancreaticobiliary Surgery, Sun Yat-sen University, Guangzhou, China.
Tan J; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
Teh BT; Oncology Academic Clinical Program, Duke-NUS Medical School, Singapore.