Eighteen iridoids from the roots and rhizomes of Valeriana jatamansi and their protective effects against α-hemolysin.
Phytochemistry
; 219: 113962, 2024 Mar.
Article
in En
| MEDLINE
| ID: mdl-38185394
ABSTRACT
Thirteen previously undescribed iridoids (1-13), together with five known iridoids (14-18) were isolated from the roots and rhizomes of Valeriana jatamansi Jones. Their structures with absolute configurations were elucidated by analysis of MS, NMR, optical rotation and their experimental and calculated electronic circular dichroism spectra. All of the isolated compounds were tested for their protective effects against α-hemolysin-induced cell death in A549 cells. Compounds 14, 16 and 17 showed moderate protective effects, and compounds 15 and 18 showed weak protective effects.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Valerian
/
Nardostachys
Language:
En
Journal:
Phytochemistry
Year:
2024
Type:
Article
Affiliation country:
China