Gender and age differences in KDIGO treatment targets among people on maintenance hemodialysis: Findings from a tertiary hospital in Vietnam.
Medicine (Baltimore)
; 103(4): e37088, 2024 Jan 26.
Article
in En
| MEDLINE
| ID: mdl-38277525
ABSTRACT
Age and gender are 2 important factors in the treatment of end-stage chronic kidney disease with hemodialysis. Understanding the influence of these 2 factors can help optimize treatment for this population. This study evaluated gender and age differences in achievement of Kidney Disease Improving Global Outcomes (KDIGO) treatment targets. A cross-sectional study was conducted on 324 chronic hemodialysis patients at a tertiary referral hospital in Ho Chi Minh City, Vietnam. KDIGO treatment targets included treatment time, prescribed Qb, treated blood volume, urea reduction ratio, spKt/V, hemoglobin, albumin, phosphorus, calcium, and parathyroid hormone. Men had significantly higher treatment time (Pâ
=â
.003), prescribed Qb (Pâ
=â
.037) and hemoglobin (Pâ
=â
.031) than women. However, women had significantly higher treated blood volume (Pâ
<â
.001), spKt/V (Pâ
<â
.001) and URR (Pâ
<â
.001). No significant difference between men and women was found in albumin, calcium, phosphorus, and parathyroid hormone. Based on KDIGO treatment targets, women had a significantly higher rate of achievement of spKt/Vâ
>â
1.2 (91.4% vs 80.7%, Pâ
=â
.005) and URRâ
≥â
70% (77.0% vs 54.7%, Pâ
<â
.001) than men. A significantly higher rate of treated volume ofâ
≥â
1 L/kg/BW, and phosphorus 2.5 to 4.6 mg/dL was found in women (90.0% and 40.2%) compared to men (68.7% and 27.3%). In contrast, men had a significantly higher rate of prescribed Qbâ
≥â
300 mL/min (26.7% vs 12.6%, Pâ
=â
.001), albuminâ
≥â
40 g/L (36.7% vs 26.4%, Pâ
=â
.047), and Hbâ
>â
12 g/dL (22.0% vs 11.5%, Pâ
=â
.011) than women. There was no significant difference between men and women in the rate of calcium 8.4 to 10.4 mg/dL, and parathyroid hormone 150 to 600 pg/mL. These differences were not the same across 4 age categories (<60, 60-69, 70-79, andâ
≥â
80). Most of the differences above were among patients agedâ
<â
60 and 60 to 69 years. Although men had higher satisfactory treatment parameters than women, based on KDIGO treatment targets, women received hemodialysis more effectively than men. Treatment targets for patients on hemodialysis should consider gender and age differences.
Full text:
1
Database:
MEDLINE
Main subject:
Kidney Diseases
/
Kidney Failure, Chronic
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Country/Region as subject:
Asia
Language:
En
Journal:
Medicine (Baltimore)
Year:
2024
Type:
Article
Affiliation country:
Vietnam