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Integrating cfDNA liquid biopsy and organoid-based drug screening reveals PI3K signaling as a promising therapeutic target in colorectal cancer.
Yang, Huan; Xiao, Xing; Zeng, Leli; Zeng, Haiteng; Zheng, Yueyuan; Wang, Jingshu; Li, Guanghua; Dai, Weigang; He, Yulong; Wang, Suihai; Peng, Jianjun; Chen, Wei.
Affiliation
  • Yang H; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Xiao X; Guangdong Provincial Key Laboratory of Digestive Cancer Research, Shenzhen, Guangdong, China.
  • Zeng L; Guangdong Provincial Key Laboratory of Digestive Cancer Research, Shenzhen, Guangdong, China.
  • Zeng H; Department of Biobank, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China.
  • Zheng Y; Guangdong Provincial Key Laboratory of Digestive Cancer Research, Shenzhen, Guangdong, China.
  • Wang J; Clinical Big Data Research Center, Scientific Research Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China.
  • Li G; Department of Oncology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Dai W; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • He Y; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Wang S; Guangdong Provincial Key Laboratory of Digestive Cancer Research, Shenzhen, Guangdong, China.
  • Peng J; Department of Gastrointestinal Surgery, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, China.
  • Chen W; School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, Guangdong, China. suihaiw65@163.com.
J Transl Med ; 22(1): 132, 2024 02 03.
Article in En | MEDLINE | ID: mdl-38310289
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Cell-Free Nucleic Acids Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: J Transl Med Year: 2024 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Cell-Free Nucleic Acids Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: J Transl Med Year: 2024 Type: Article Affiliation country: China