Yin Yang 1 facilitates the activation, inflammation, and extracellular matrix deposition of hepatic stellate cells in hepatic fibrosis.

Fu, Xiao; Luo, Xin; Xiao, Ping; Guo, Ninghong

Fu, Xiao; Luo, Xin; Xiao, Ping; Guo, Ninghong.

Affiliation

Fu X; General Medicine Department, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, People's Republic of China.
Luo X; General Medicine Department, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, People's Republic of China.
Xiao P; General Medicine Department, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, People's Republic of China.
Guo N; Clinical Trial Center, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, People's Republic of China.

Pathol Int ; 74(4): 197-209, 2024 Apr.

Article in En | MEDLINE | ID: mdl-38353379

Subject(s)

Proto-Oncogene Proteins c-akt; Transforming Growth Factor beta1; Humans; Rats; Animals; Transforming Growth Factor beta1/metabolism; Transforming Growth Factor beta1/pharmacology; Transforming Growth Factor beta1/therapeutic use; Hepatic Stellate Cells/metabolism; Hepatic Stellate Cells/pathology; Phosphatidylinositol 3-Kinases/metabolism; Phosphatidylinositol 3-Kinases/pharmacology; Phosphatidylinositol 3-Kinases/therapeutic use; Yin-Yang; Liver Cirrhosis/metabolism; Extracellular Matrix/metabolism; Inflammation/metabolism; Carbon Tetrachloride

Key words

Yin Yang 1; chronic hepatic disease; extracellular matrix deposition; hepatic fibrosis; inflammation

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Full text: 1 Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_china Main subject: Proto-Oncogene Proteins c-akt / Transforming Growth Factor beta1 Type of study: Prognostic_studies Language: En Journal: Pathol Int Year: 2024 Type: Article

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