Prebiotics and Probiotics for Gastrointestinal Disorders.
Nutrients
; 16(6)2024 Mar 09.
Article
in En
| MEDLINE
| ID: mdl-38542689
ABSTRACT
The complex role of the gut microbiome in the pathogenesis of gastrointestinal (GI) disorders is an emerging area of research, and there is considerable interest in understanding how diet can alter the composition and function of the microbiome. Prebiotics and probiotics have been shown to beneficially modulate the gut microbiome, which underlies their potential for benefit in GI conditions. Formulating specific recommendations for the public regarding these dietary supplements has been difficult due to the significant heterogeneity between strains, doses, and duration of treatment investigated across studies, as well as safety concerns with administering live organisms. This review aims to summarize the existing evidence for the use of prebiotics and probiotics in various GI disorders, paying special attention to strain-specific effects that emerged and any adverse effects noted.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Probiotics
/
Irritable Bowel Syndrome
/
Gastrointestinal Diseases
Language:
En
Journal:
Nutrients
Year:
2024
Type:
Article
Affiliation country:
United States