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Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival.
Goswami, Moloy T; Weh, Eric; Subramanya, Shubha; Weh, Katherine M; Durumutla, Hima Bindu; Hager, Heather; Miller, Nicholas; Chaudhury, Sraboni; Andren, Anthony; Sajjakulnukit, Peter; Zhang, Li; Besirli, Cagri G; Lyssiotis, Costas A; Wubben, Thomas J.
Affiliation
  • Goswami MT; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Weh E; equal contribution.
  • Subramanya S; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Weh KM; equal contribution.
  • Durumutla HB; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Hager H; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Miller N; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Chaudhury S; Molecular and Developmental Biology Graduate Program, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Andren A; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Sajjakulnukit P; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Zhang L; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
  • Besirli CG; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Lyssiotis CA; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
  • Wubben TJ; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
bioRxiv ; 2024 Jul 01.
Article in En | MEDLINE | ID: mdl-38586045

Full text: 1 Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Type: Article Affiliation country: United States