The latest emerging drugs for the treatment of diabetic cardiomyopathy.
Expert Opin Pharmacother
; 25(6): 641-654, 2024 Apr.
Article
in En
| MEDLINE
| ID: mdl-38660817
ABSTRACT
INTRODUCTION:
Diabetic cardiomyopathy (DCM) is a serious complication of diabetes mellitus involving multiple pathophysiologic mechanisms. In addition to hypoglycemic agents commonly used in diabetes, metabolism-related drugs, natural plant extracts, melatonin, exosomes, and rennin-angiotensin-aldosterone system are cardioprotective in DCM. However, there is a lack of systematic summarization of drugs for DCM. AREAS COVERED In this review, the authors systematically summarize the most recent drugs used for the treatment of DCM and discusses them from the perspective of DCM pathophysiological mechanisms. EXPERT OPINION We discuss DCM drugs from the perspective of the pathophysiological mechanisms of DCM, mainly including inflammation and metabolism. As a disease with multiple pathophysiological mechanisms, the combination of drugs may be more advantageous, and we have discussed some of the current studies on the combination of drugs.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Diabetic Cardiomyopathies
/
Hypoglycemic Agents
Language:
En
Journal:
Expert Opin Pharmacother
Year:
2024
Type:
Article
Affiliation country:
China