Immunoliposomes in vivo.
Immunomethods
; 4(3): 259-72, 1994 Jun.
Article
in En
| MEDLINE
| ID: mdl-7820456
ABSTRACT
Attachment of antibodies to the surface of liposomes was performed to confer specificity for a certain cell or organ expressing the targeted antigenic determinant. These so-called immunoliposomes are expected to be applied as targeted drug carriers. In this article, the literature concerning in vivo studies of the targeting of immunoliposomes to various sites in the body is reviewed. The anatomical, physiological, and pathological constraints and current progress are described. Moreover, perspectives on the therapeutic feasibility of this drug targeting system are discussed.
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Database:
MEDLINE
Main subject:
Immunoconjugates
/
Liposomes
Language:
En
Journal:
Immunomethods
Year:
1994
Type:
Article
Affiliation country:
Netherlands