Ascorbate-dependent elevation of mRNA levels for cytochrome P450s induced by polychlorinated biphenyls.

Suzuki, H; Torii, Y; Hitomi, K; Tsukagoshi, N

Suzuki, H; Torii, Y; Hitomi, K; Tsukagoshi, N.

Affiliation

Suzuki H; Department of Applied Biological Sciences, Faculty of Agriculture, Nagoya University, Japan.

Biochem Pharmacol ; 46(1): 186-9, 1993 Jul 06.

Article in En | MEDLINE | ID: mdl-8347131

Subject(s)

Ascorbic Acid Deficiency/genetics; Bone Diseases, Developmental/genetics; Cytochrome P-450 Enzyme System/genetics; Isoenzymes/genetics; Liver/drug effects; Polychlorinated Biphenyls/toxicity; RNA, Messenger/analysis; Animals; Ascorbic Acid/analysis; Ascorbic Acid/pharmacology; Bone Diseases, Developmental/chemically induced; Cytochrome P-450 Enzyme System/biosynthesis; Enzyme Induction/drug effects; Isoenzymes/biosynthesis; Liver/metabolism; Male; RNA, Messenger/isolation & purification; Rats; Rats, Mutant Strains

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Database: MEDLINE Main subject: Ascorbic Acid Deficiency / Bone Diseases, Developmental / RNA, Messenger / Polychlorinated Biphenyls / Cytochrome P-450 Enzyme System / Isoenzymes / Liver Language: En Journal: Biochem Pharmacol Year: 1993 Type: Article Affiliation country: Japan

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