The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers.

Pozos, T C; Sekler, I; Cyert, M S

Pozos, T C; Sekler, I; Cyert, M S.

Affiliation

Pozos TC; Department of Biological Sciences, Stanford University, California 94305-5020, USA.

Mol Cell Biol ; 16(7): 3730-41, 1996 Jul.

Article in En | MEDLINE | ID: mdl-8668190

Subject(s)

Antiporters/genetics; Antiporters/metabolism; Calcium/metabolism; Genes, Fungal; Saccharomyces cerevisiae Proteins; Saccharomyces cerevisiae/metabolism; Adenosine Triphosphatases/metabolism; Amino Acid Sequence; Animals; Antiporters/chemistry; Base Sequence; Calcineurin; Calmodulin-Binding Proteins/genetics; Calmodulin-Binding Proteins/metabolism; Carrier Proteins/chemistry; Carrier Proteins/genetics; Cattle; Dogs; Genomic Library; Genotype; Intracellular Membranes/drug effects; Intracellular Membranes/metabolism; Mammals; Molecular Sequence Data; Myocardium/metabolism; Nigericin/pharmacology; Phenotype; Phosphoprotein Phosphatases/genetics; Phosphoprotein Phosphatases/metabolism; Restriction Mapping; Retina/metabolism; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/growth & development; Sequence Homology, Amino Acid; Sodium-Calcium Exchanger; Vacuoles/metabolism

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Full text: 1 Database: MEDLINE Main subject: Saccharomyces cerevisiae / Calcium / Antiporters / Saccharomyces cerevisiae Proteins / Genes, Fungal Type of study: Prognostic_studies Language: En Journal: Mol Cell Biol Year: 1996 Type: Article Affiliation country: United States

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