Preclinical pharmacokinetics and distribution to tissue of AG1343, an inhibitor of human immunodeficiency virus type 1 protease.

Shetty, B V; Kosa, M B; Khalil, D A; Webber, S

Shetty, B V; Kosa, M B; Khalil, D A; Webber, S.

Affiliation

Shetty BV; Department of Pharmacology, Agouron Pharmaceuticals, Inc., San Diego, California 92121, USA. shetty@agouron.com

Antimicrob Agents Chemother ; 40(1): 110-4, 1996 Jan.

Article in En | MEDLINE | ID: mdl-8787890

Subject(s)

HIV Protease Inhibitors/pharmacokinetics; HIV-1/enzymology; Isoquinolines/pharmacokinetics; Sulfonic Acids/pharmacokinetics; Administration, Oral; Animals; Callithrix; Dogs; Drug Evaluation, Preclinical; Female; HIV Protease Inhibitors/administration & dosage; Injections, Intravenous; Isoquinolines/administration & dosage; Macaca fascicularis; Male; Nelfinavir; Rats; Rats, Sprague-Dawley; Species Specificity; Sulfonic Acids/administration & dosage; Tissue Distribution

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Full text: 1 Database: MEDLINE Main subject: Sulfonic Acids / HIV-1 / HIV Protease Inhibitors / Isoquinolines Type of study: Prognostic_studies Language: En Journal: Antimicrob Agents Chemother Year: 1996 Type: Article Affiliation country: United States

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