Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase.

Gong, Q; White, L; Johnson, R; White, M; Negishi, I; Thomas, M; Chan, A C

Gong, Q; White, L; Johnson, R; White, M; Negishi, I; Thomas, M; Chan, A C.

Affiliation

Gong Q; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Immunity ; 7(3): 369-77, 1997 Sep.

Article in En | MEDLINE | ID: mdl-9324357

Subject(s)

Enzyme Precursors/physiology; Protein-Tyrosine Kinases/physiology; T-Lymphocytes/physiology; Thymus Gland/growth & development; Animals; DNA, Complementary/genetics; DNA, Complementary/metabolism; Enzyme Precursors/biosynthesis; Enzyme Precursors/genetics; Epithelium/growth & development; Epithelium/ultrastructure; Female; Gene Expression; Humans; Intestines/growth & development; Intestines/ultrastructure; Intracellular Signaling Peptides and Proteins; Leukocyte Common Antigens/genetics; Leukocyte Common Antigens/physiology; Mice; Mice, Inbred C57BL; Protein-Tyrosine Kinases/biosynthesis; Protein-Tyrosine Kinases/genetics; Receptors, Antigen, T-Cell, gamma-delta/biosynthesis; Receptors, Antigen, T-Cell, gamma-delta/physiology; Signal Transduction/physiology; Syk Kinase; T-Lymphocytes/cytology; T-Lymphocytes/ultrastructure; Thymus Gland/cytology; Thymus Gland/ultrastructure; Transgenes; ZAP-70 Protein-Tyrosine Kinase

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Database: MEDLINE Main subject: Thymus Gland / Protein-Tyrosine Kinases / T-Lymphocytes / Enzyme Precursors Language: En Journal: Immunity Year: 1997 Type: Article Affiliation country: United States

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