Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice.

Sato, Y; Ferguson, D G; Sako, H; Dorn, G W; Kadambi, V J; Yatani, A; Hoit, B D; Walsh, R A; Kranias, E G

Sato, Y; Ferguson, D G; Sako, H; Dorn, G W; Kadambi, V J; Yatani, A; Hoit, B D; Walsh, R A; Kranias, E G.

Affiliation

Sato Y; Department of Pharmacology and Cell Biophysics, University of Cincinnati, Cincinnati, Ohio 45267, USA.

J Biol Chem ; 273(43): 28470-7, 1998 Oct 23.

Article in En | MEDLINE | ID: mdl-9774476

Subject(s)

Calsequestrin/metabolism; Cardiomegaly; Myocardial Contraction; Ventricular Function, Left; Amino Acid Sequence; Animals; Base Sequence; Calcium Channels/metabolism; Calsequestrin/genetics; Cells, Cultured; DNA, Complementary/genetics; Gene Expression; Gene Expression Regulation, Developmental; Gene Library; In Vitro Techniques; Mice; Mice, Transgenic; Molecular Sequence Data; Myocardium/cytology; Myocardium/ultrastructure; Perfusion; Recombinant Proteins/metabolism; Sarcoplasmic Reticulum/metabolism; Sodium-Calcium Exchanger/metabolism

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Database: MEDLINE Main subject: Calsequestrin / Ventricular Function, Left / Cardiomegaly / Myocardial Contraction Type of study: Risk_factors_studies Language: En Journal: J Biol Chem Year: 1998 Type: Article Affiliation country: United States

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