Hepatoprotective and nitric oxide production inhibitory activities of coumarin and polyacetylene constituents from the roots of Angelica furcijuga.

Matsuda, H; Murakami, T; Kageura, T; Ninomiya, K; Toguchida, I; Nishida, N; Yoshikawa, M

Matsuda, H; Murakami, T; Kageura, T; Ninomiya, K; Toguchida, I; Nishida, N; Yoshikawa, M.

Affiliation

Matsuda H; Kyoto Pharmaceutical University, Japan.

Bioorg Med Chem Lett ; 8(16): 2191-6, 1998 Aug 18.

Article in En | MEDLINE | ID: mdl-9873511

Subject(s)

Acetylene/analogs & derivatives; Coumarins/pharmacology; Galactosamine/antagonists & inhibitors; Liver/drug effects; Macrophages, Peritoneal/physiology; Nitric Oxide/metabolism; Plants, Medicinal; Polymers/pharmacology; Acetylene/chemistry; Acetylene/isolation & purification; Acetylene/pharmacology; Animals; Cell Survival/drug effects; Cells, Cultured; Coumarins/chemistry; Coumarins/isolation & purification; Diynes; Fatty Alcohols/chemistry; Fatty Alcohols/isolation & purification; Fatty Alcohols/pharmacology; Galactosamine/toxicity; Japan; Lipopolysaccharides/toxicity; Liver/cytology; Liver/pathology; Macrophages, Peritoneal/drug effects; Medicine, Traditional; Mice; Molecular Structure; Plant Extracts; Plant Roots; Polymers/chemistry; Polymers/isolation & purification; Polyynes; Rats; Structure-Activity Relationship

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Database: MEDLINE Traditional Medicines: Medicinas_tradicionales_de_asia / Medicina_japonesa Therapeutic Methods and Therapies TCIM: Terapias_biologicas / Plantas_medicinales Main subject: Plants, Medicinal / Polymers / Acetylene / Macrophages, Peritoneal / Coumarins / Galactosamine / Liver / Nitric Oxide Country/Region as subject: Asia Language: En Journal: Bioorg Med Chem Lett Year: 1998 Type: Article Affiliation country: Japan

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