Studies on chemical constituents of Sarcandra glabra / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 900-902, 2008.
Article
in Zh
| WPRIM
| ID: wpr-295445
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study antibacterial chemical constituents of Sarcandra glabra.</p><p><b>METHOD</b>The constituents of the chloroform and EtOAc-soluble portions of the EtOH extract from the whole plant of S. glabra, which posses the antibacterial activities, were isolated and purified with column chromatography. The compounds were identified by physical and spectroscopic techniques.</p><p><b>RESULT</b>Six compounds were isolated and identified as 4, 4'-biisofraxidin (1), esculetin (2), fraxetin (3), scoparone (4), isofraxidin (5), scopoletin(6), respectively.</p><p><b>CONCLUSION</b>Compound 1 is a novel natural product. Compounds 24 were isolated from the plants of Chloranthaceae for the first time. The antibacterial activities of these six compounds were tested for the first time. Some compounds may have potential for future study and development as plant-derived oral antibacterial agents.</p>
Full text:
1
Database:
WPRIM
Traditional Medicines:
Medicinas_tradicionales_de_asia
/
Medicina_china
Main subject:
Pharmacology
/
Spectrophotometry, Infrared
/
Streptococcus mutans
/
Drugs, Chinese Herbal
/
Magnetic Resonance Spectroscopy
/
Chemistry
/
Porphyromonas gingivalis
/
Magnoliopsida
/
Coumarins
/
Spectrometry, Mass, Electrospray Ionization
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Type:
Article