Optimization of extraction process of Chrysanthemi Flos by multi-index orthogonal experiment / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 821-824, 2013.
Article
in Zh
| WPRIM
| ID: wpr-318637
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore quantitative assessment indicators of Chrysanthemi Flos, and optimize the extraction process of Chrysanthemi Flos through orthogonal experimental design.</p><p><b>METHOD</b>The concentration of ethanol, amount of ethanol, extraction time and extraction frequency were selected as factors in the L9 (3(4)) orthogonal experiment. A comprehensive assessment was conducted with the peak area of the eight major common peaks in the fingerprint of Chrysanthemi Flos as the indicators.</p><p><b>RESULT</b>The optimum extraction process was selected as follows: using ultrasonic extraction method, adding 30-fold ethanol with 80% concentration, extracting for 2 times for extraction, 40 min for each time.</p><p><b>CONCLUSION</b>The optimized extraction process is reliable, with controllable assessment indicators, which is significant to the standardization of the extraction process and quality control of Chrysanthemi Flos preparations.</p>
Full text:
1
Database:
WPRIM
Traditional Medicines:
Medicinas_tradicionales_de_asia
/
Medicina_china
Main subject:
Quality Control
/
Solubility
/
Time Factors
/
Drugs, Chinese Herbal
/
Chemistry
/
Reproducibility of Results
/
Chrysanthemum
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Ethanol
/
Chemical Fractionation
/
Hot Temperature
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article