Real-time detection of quality of Chinese materia medica: strategy of NIR model evaluation / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2774-2781, 2015.
Article
in Zh
| WPRIM
| ID: wpr-337892
Responsible library:
WPRO
ABSTRACT
The definition of critical quality attributes of Chinese materia medica ( CMM) was put forward based on the top-level design concept. Nowadays, coupled with the development of rapid analytical science, rapid assessment of critical quality attributes of CMM was firstly carried out, which was the secondary discipline branch of CMM. Taking near infrared (NIR) spectroscopy as an example, which is a rapid analytical technology in pharmaceutical process over the past decade, systematic review is the chemometric parameters in NIR model evaluation. According to the characteristics of complexity of CMM and trace components analysis, a multi-source information fusion strategy of NIR model was developed for assessment of critical quality attributes of CMM. The strategy has provided guideline for NIR reliable analysis in critical quality attributes of CMM.
Full text:
1
Database:
WPRIM
Traditional Medicines:
Medicinas_tradicionales_de_asia
/
Medicina_china
Complementary Medicines:
Homeopatia
Main subject:
Reference Standards
/
Materia Medica
/
Spectroscopy, Near-Infrared
/
Medicine, Chinese Traditional
/
Methods
Type of study:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2015
Type:
Article