N-containing compounds from seeds of Paganum harmala / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1601-1606, 2019.
Article
in Zh
| WPRIM
| ID: wpr-774516
Responsible library:
WPRO
ABSTRACT
To investigate the N-containing compounds in the seeds of Paganum harmala,fourteen compounds were finally isolated from the 95% Et OH extract of P. harmala seeds by using various chromatographic techniques including silica gel,MCI resin,and ODS column chromatography as well as the semi-preparative HPLC. Depending on spectroscopic techniques and comparison with the reported data in the literatures,the structures of all compounds were identified as N-[3-(2-amino-4-methoxyphenyl)-3-oxopropyl]acetamide(1),dehydroharmalacidine(2),harmalacidine(3),harmine N-oxide(4),harmine(5),tetrahydroharmine(6),demethylharmalacidine(7),harmol(8),tetrahydroharmol(9),harmindol β-D-glucopyranoside(10),tryptophyl β-D-glucopyranoside(11),pegamineβ-D-glucopyranoside(12),vasicol(13) and vasicinone(14). Among them,1 was a new compound,and 2 and 10 were obtained as natural products for the first time.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Seeds
/
Plant Extracts
/
Chemistry
/
Chromatography, High Pressure Liquid
/
Peganum
/
Phytochemicals
/
Nitrogen
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2019
Type:
Article